Wheat dextrin can interfere with the absorption of calcium, iron, zinc, and vitamin B12; and may also affect anticoagulants, antidepressants, anti-gout agents, anti-inflammatory agents, diuretics, salicylates, tetracyclines, nitrofurantoin, insulin, lithium, and digoxin. I suggest taking medication or vitamins one hour before, or a few hours after, wheat dextrin to help prevent interactions. To be safe, patients should be monitored for changes in medication requirements following the initiation of fiber therapy. Also keep in mind, the Belly Fat Cure™ Drink accounts for two of your daily carb servings.